PRODUCTS AND SERVICES
Values, Culture and Strengths:
Our diverse collections of individually crafted molecules are primarily generated in our proprietary state-of-the-art research laboratories that employ over 40 experienced chemists. IVK Labs professional staff is constructed around a core of scientists and professionals with significant experience in biotechnology as well as in
pharmaceutical chemical research and development. Their response to our customer’s needs are guided by our management team and supported by administrative personnel.
While some companies view their reactors and expensive equipment as their most important assets, we do not. Our most important assets are our people! We have focused on building our company around accomplished and highly qualified scientists. Over 20 Ph.D./M.S. chemists are involved in the research-intensive combinatorial product development, production and drug discovery collaborations.
Our core values, culture and strengths include:
• Highest scientific, ethical and quality standards
• Strong emphasis on customer service
• Outstanding management team and culture
• Problem solving and technology capabilities
We are well known for our flexible business models in work with customers and high hit rates in many screens. Our chemistry-focused technology platform strategically positions IVK Labs to comprehensively support the chemistry side of new lead identification and optimization in the pharmaceutical and biotechnology industries. If you are a customer, you’ll be glad to know that at ILK Labs we have established long-term relationships and an impeccable reputation with our clients.
Reagents and Building Blocks:
The pursuit of new drug-like structures cannot be imagined without constant influx of highly versatile sets of compounds used to build up combinatorial libraries.
Nowadays, with combinatorial chemistry quickly becoming a leading chemical technology in the foundation of modern drug discovery programs, the industry starts to face some significant limitations in its combinatorial chemistry efforts. Despite the large number of catalog reagents, the selection of truly desirable compounds that are the most useful as building blocks for combinatorial chemistry is quite limited. The industry has clearly understood that an extensive portfolio of unique combinatorial building blocks is a key element of an enabling chemistry platform and a crucially important competitive advantage for lead generation, hit-to-lead and lead optimization programs.
The primary goal of IVK Labs is to accelerate and facilitate the drug discovery process by providing combinatorial and pharmaceutical laboratories with rare building blocks bearing highly pharmacophoric fragments.
We have successfully created a unique collection of building blocks representing different structural classes of compounds that can meet the most demanding requirements of any pharmaceutical laboratory working in the field of combinatorial or medicinal chemistry.
Listed below are the structural classes of the compounds that we include in our collection because of their great potential as scaffolds for combinatorial libraries: various heterocyclic and non-heterocyclic derivatives containing fragments of benzothiazoles, furanes, indoles, izoxazoles, piperidines, pyrazoles, pyridines, pyrimidines, pyrroles, pyrrolidines, quinolines, thiadiazoles, thiazoles, thiophenes, triazines, triazoles and others.
More than 5,000 compounds from our collection of building blocks are ready to be delivered to the customers within a matter of days. We offer over 1,000 building blocks that are proprietary and not available from elsewhere. All of our building blocks have a minimum purity of 95%.
We are open to any kind of collaboration and exchange of ideas in the areas of custom synthesis, lead optimization, designing new libraries using our building blocks as scaffolds. After all, playing with molecules—is our specialty.
Virtual Library:
Our company has assembled a virtual library of more than 2 million compounds. This is a continually growing database. On average we deliver about 80% of your combined choices of 5,000 samples or more a month out of our virtual library. Our competitors only average at around 50-60%.
Custom Synthesis:
Using our expertise in organic chemistry we provide unique state-of-the-art solutions for those of our clients who are interested in custom synthesis both on a FTE basis and on a cost per compound basis. Regardless of the chosen scheme IVK Labs ensures a smooth collaboration and is proud of its flexible approach towards our outsourcing partners. Our services that include molecular design and modifications as well as custom synthesis of standards for neuropharmaceutical applications and compounds with specified pharmacophoric fragments and have been used by several biotech and pharmaceutical companies. These services help our customers to create a unique, selection of compounds, using either the client’s requested properties, fingerprints or actual structures.
IVK Labs is committed to save your scientists valuable time in yielding a rational library, designated especially for our clients.
Quality:
Product quality is of utmost importance to us. We are acutely aware of the time, effort and money our customers invest in their work. Poor quality reagents can ruin even the best-designed experiments. Our commitment to quality is a direct result of this awareness. From receiving dock to the shipping dock, we have developed exhaustive
quality assurance protocol. Starting with the basic raw materials and ending with the final highly purified end product, we maintain purity and quality documentation.
All compounds we offer are subject to an extensive 100% NMR quality control confirming their identity and purity. Spectra interpretation and final approval of each compound are executed by a dedicated group of Ph.D. analytical chemists, with only compounds over 90% purity or greater being retained. The actual data shows that over 60% of our compounds have purity over 95% and all of them greater than 90%. If requested, the original NMR/MS spectra for all compounds are available.
IVK Labs also welcomes the independent testing of all compounds supplied to our customers and abides by its own tough internal standards to ensure that our customers receive only the superior quality products.